What is different about Hard Mode?

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Binding of Isaac got an update last night, it now contains a "Hard Mode".
I've started a game with it, and so far I've noticed a couple new types of champions, more champions and a bomb that turned into a live bomb when I tried to pick it up. I'm not sure if all of this is caused by Hard Mode or just by the update (I assume the more champions is caused by Hard Mode though)
Are there any other differences? Less drops? Champion types unique to Hard Mode? Special bosses? Other rooms?
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What is the difference between Hardmode and normal?
Hard is a more difficult mode than Normal. In Hard mode, hostile mobs will spawn and deal more damage than Normal mode. Mobs can cause you harmful status effects such as Poison or the Wither effect. You will take damage from the physical world such as lava, drowning, or fall damage.What is different in Hardmode binding of Isaac?
Hard Mode is a mode added to the Eternal Edition update for the original game. It changes the gameplay in certain ways to make it harder. When playing in hard mode, a little red pentagram appears on the HUD, below the consumables. Rooms contain more advanced enemies and in a higher number.Does Isaac Hardmode give better items?
Basically what you experienced. Hard mode makes keys/bombs less common, more champion enemies/bosses, and special item drops become a LOT more rare.What does Hardmode unlock?
Most Hard mode unlocks are co-op babies, with the notable exceptions of Godhead, Smelter, Marrow, Mega Mush, Death Certificate and the character.Why Hard Difficulty In Minecraft Is Actually EASIER
Sources: Stack Exchange - This article follows the attribution requirements of Stack Exchange and is licensed under CC BY-SA 3.0.
Images: Erik Mclean, Karolina Grabowska, Alfo Medeiros, Scott Webb