What is the best way to obtain a ridiculously high score in Goat Ville?

The best thing to do is to take a visit to the Low Gravity Testing Facility (found next to one of the tunnel entrances). You can either jump over the fence by the garage by jumping on the boxes stacked up next to it, or by climbing onto the sloped rocks by the goalposts and jumping over there, or walk though a hole in the fence by the gate (I only just noticed this...). Headbutt the brown panel to get yourself in, the walk up the slope to the right, enter the Low Gravity tank and go mental. Hold right-click and use the arrow keys to do front, side, and backflips, and the score will stack until you hit the ground, resulting in a ridiculously high score and something along the lines of a "Integer Overflowduple Backflip."

Do this a few times and you'll be there in no time.

Alright, so after some time spent researching in game. (Mostly consisting of jumping on and licking things. It looks like the quickest way to get a high score is to use the "Wonder Of Science" hole shown below similar to using a trampoline, in the fact that you constantly hold down right mouse button and two non-competing movement keys ((Aka w+d, a+w, a+s, s+d)) but with less likelihood of missing the fall back down. I was able to get several hundred thousand in a combo, and it can theoretically keep going higher. The one downside of using this is that you do have to keep adjusting your fall by letting go of the right mouse button somewhat, otherwise you'll ragdoll due to hitting the side of the top of the hole and be unable to continue your combo, but it's far easier to land back down on the fan inside than on a trampoline due to the walls.

Alternatively, a more fun, but very much less efficient method, generally resulting in 10000 - 40000 a shot is by glitching out the car that moves along the road. If you lick the car, it will take you into the tunnel, but keep you pressed against the back wall of the tunnel for a short time. Once the car disappears completely, you will go flying through the map, generally, as previously said, picking up a 10000-40000 score. You don't even have to lick the car while it's moving, as once in the tunnel, it'll stay just at the very edge of the tunnel for a short time, as shown below ((Brightness and contrast adjusted for maximum visibility)). It's hilarious to see what happens each time, but as mentioned, it's a lot less efficient than the first method.

The trick I've found to getting points quickly is to get the Angel Goat mutator by not damaging anything for five minutes. There's also a spot in the Construction Site where there are mattresses on the ceiling and on the floor, which allow you to bounce insanely fast and get a crapload of points. Anyway, the Angel Goat mutator means that if you bounce off of fans and hold R, you stay airborne for a stupidly long time. If you hold A and W and RMB, you can get ridiculous numbers of points when you land.

If tombull's answer has been patched, one of the best ways to get a high score is to go to a location with a large number of items in a confined place, and start kicking, licking and headbutting everything. You should be able to get up to a 15x multiplier each time for each of these actions. Alternatively, you can try looking for areas with repeatable 'purple' score modifiers, as these tend to give a larger number of points, and try and chain these with flips, headbutts, kicks, and licks, to try and combine the large number of points from purple score modifiers with high multipliers. The big issue with this is that most repeatable 'purple' score modifiers are in places where there's not much else around, so chaining these together can be quite difficult.

Alternatively, Goat Simulator is a very buggy game, and it is possible to glitch out to start racking up massive amounts of points. I had a glitch occur where I was able to keep getting 24x combos with about 10-15 'purple' score modifiers just by being stuck in the air. I've tried to replicate this glitch, but have been unsuccessful thus far. Just keep an eye out for this kind of thing happening while you play, and take full advantage of it when you can.

Way too simple.

Use custom map, add Feather mutator. Being an ostritch lick anything and keep it licked. Jump straight up (preferably in a cleared area) and hold right mouse button, all the while you hit either A for left or D for right. And Keep stupidly jumping.

If you time it right, the ostritch will not touch the foor, thereby givin you more spins.

Do this several times untill you touch the floor, then it wil say something like; 48907 points 6087 spin x1

That is when you make sure to touch the floor so the x1 becomes x10 or even x15.

I don't know if this exists on the PC version, but on the IOS version, there is a cafe at the edge of the ocean, at the bottom of the tower. In there, you can find slot machines. When the game tells you to press your special move key, do so. If three of the same pieces are aligned, you will get a 1 000 000 point bonus that you can then easily multiply. The images align roughly 1/3 times, and the thing takes 10 seconds to spin, so can easily rack up 50 million points in two or three minutes.