Can you kill all non-quest NPC's permanently

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I'd like to start recording some Fallout NV, in which I'd naturally discover each location and murder that locations population.
So if I was to do this, if I returned to the locations which I discovered, would the non-quest NPC's still be dead or would they respawn.
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What happens if you kill a NPC in Elden ring?
If you kill him before completing his questline, the game will lock you out of his quest that leads to the best farming method in the game. You'll need to start a new game if you want to complete his quest. Elden Ring supports multiple characters and multiple saves. You can start a new game if you killed the wrong NPC.What happens if you kill important NPCs in Skyrim?
What you need to take note of is if you kill Anyone and a law abiding NPC sees it you will have a bounty due to that and all law abiding npcs will attack you ... and it may only be an accidental hit. Check your Crime level in the main menu and it will tell you how big your bounty is and in which hold.Can you kill NPC in Fallout 4?
Some people in Fallout 4 are invunerable. You can use a console command to make them killable. Exact quote from the wiki: setessential <baseID> <bool> \u2013 Allows an NPC to be permanently killed or alternatively - unable to be killed, depending on the value used (see below).Who is unkillable in Fallout New Vegas?
Heard that there were only 2 unkillable things in New Vegas, and I want to know what they are. Yes Man - because he keeps respawning if you kill him. The vending robot at Gun Runner's - because he is behind glass. And the kids.what happens if you kill (almost) every npc in elden ring
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