How do I make a setblock or a fill clock?

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Often, when asking about command block contraptions, people suggest using a "setblock" or "fill" clock?
What are those and how do I make them?
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How do you make a fill up clock?
How to Enter the CommandHow to use the /FILL command in Minecraft! (1.16.1+)
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Images: Brett Jordan, Brett Jordan, Sora Shimazaki, Yan Krukov